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Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses

Neuroligins are postsynaptic cell-adhesion molecules that bind presynaptic neurexins and are genetically linked to autism. Neuroligins are proposed to organize synaptogenesis and/or synaptic transmission, but no systematic analysis of neuroligins in a defined circuit is available. Here, we show that...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Zhang, Bo, Chen, Lulu Y., Liu, Xinran, Maxeiner, Stephan, Lee, Sung-Jin, Gokce, Ozgun, Südhof, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545494/
https://ncbi.nlm.nih.gov/pubmed/26291161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.07.020
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