Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux

Differentiation of human pluripotent stem cells (hPSCs) in vitro offers a way to study cell types that are not accessible in living patients. Previous research suggests that hPSCs generate ATP through anaerobic glycolysis, in contrast to mitochondrial oxidative phosphorylation (OXPHOS) in somatic ce...

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Bibliografski detalji
Izdano u:Stem Cells Dev
Glavni autori: O'Brien, Laura C., Keeney, Paula M., Bennett, James P.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Original Research Reports
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545371/
https://ncbi.nlm.nih.gov/pubmed/25892363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0076
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