Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux

Differentiation of human pluripotent stem cells (hPSCs) in vitro offers a way to study cell types that are not accessible in living patients. Previous research suggests that hPSCs generate ATP through anaerobic glycolysis, in contrast to mitochondrial oxidative phosphorylation (OXPHOS) in somatic ce...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Dev
Autori principali: O'Brien, Laura C., Keeney, Paula M., Bennett, James P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2015
Soggetti:
Original Research Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545371/
https://ncbi.nlm.nih.gov/pubmed/25892363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0076
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