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Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux

Differentiation of human pluripotent stem cells (hPSCs) in vitro offers a way to study cell types that are not accessible in living patients. Previous research suggests that hPSCs generate ATP through anaerobic glycolysis, in contrast to mitochondrial oxidative phosphorylation (OXPHOS) in somatic ce...

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Détails bibliographiques
Publié dans:Stem Cells Dev
Auteurs principaux: O'Brien, Laura C., Keeney, Paula M., Bennett, James P.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545371/
https://ncbi.nlm.nih.gov/pubmed/25892363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0076
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