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Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux
Differentiation of human pluripotent stem cells (hPSCs) in vitro offers a way to study cell types that are not accessible in living patients. Previous research suggests that hPSCs generate ATP through anaerobic glycolysis, in contrast to mitochondrial oxidative phosphorylation (OXPHOS) in somatic ce...
Gespeichert in:
Veröffentlicht in: | Stem Cells Dev |
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Hauptverfasser: | , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Mary Ann Liebert, Inc.
2015
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545371/ https://ncbi.nlm.nih.gov/pubmed/25892363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0076 |
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