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Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux

Differentiation of human pluripotent stem cells (hPSCs) in vitro offers a way to study cell types that are not accessible in living patients. Previous research suggests that hPSCs generate ATP through anaerobic glycolysis, in contrast to mitochondrial oxidative phosphorylation (OXPHOS) in somatic ce...

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Bibliografiske detaljer
Udgivet i:Stem Cells Dev
Main Authors: O'Brien, Laura C., Keeney, Paula M., Bennett, James P.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545371/
https://ncbi.nlm.nih.gov/pubmed/25892363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0076
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