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Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma

BACKGROUND: Neuroblastoma currently has poor prognosis, therefore we proposed a new strategy by targeting neuroblastoma with genetically engineered anaerobic Salmonella (Sal-YB1). METHODS: Nude and nonobese diabetic-severe combined immunodeficiency (NOD-SCID) orthotopic mouse models were used, and S...

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Bibliografski detalji
Izdano u:J Hematol Oncol
Glavni autori: Guo, Zhu-Ling, Yu, Bin, Ning, Bo-Tao, Chan, Shing, Lin, Qiu-Bin, Li, James Chun-Bong, Huang, Jian-Dong, Chan, Godfrey Chi-Fung
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545364/
https://ncbi.nlm.nih.gov/pubmed/26286454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0196-3
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