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Explicit hypoxia targeting with tumor suppression by creating an “obligate” anaerobic Salmonella Typhimurium strain

Using bacteria as therapeutic agents against solid tumors is emerging as an area of great potential in the treatment of cancer. Obligate and facultative anaerobic bacteria have been shown to infiltrate the hypoxic regions of solid tumors, thereby reducing their growth rate or causing regression. How...

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Detalhes bibliográficos
Main Authors: Yu, Bin, Yang, Mei, Shi, Lei, Yao, Yandan, Jiang, Qinqin, Li, Xuefei, Tang, Lei-Han, Zheng, Bo-Jian, Yuen, Kwok-Yung, Smith, David K., Song, Erwei, Huang, Jian-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365283/
https://ncbi.nlm.nih.gov/pubmed/22666539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00436
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