Feedback Mechanisms for Cardiac-Specific microRNAs and cAMP Signaling in Electrical Remodeling

BACKGROUND: Loss of transient outward K(+) current (I(to)) is well documented in cardiac hypertrophy and failure both in animal models and humans. Electrical remodeling contributes to prolonged action potential duration (APD) and increased incidence of arrhythmias. Furthermore, there is a growing bo...

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Detalhes bibliográficos
Publicado no:Circ Arrhythm Electrophysiol
Main Authors: Myers, Richard, Timofeyev, Valeriy, Li, Ning, Kim, Catherine, Ledford, Hannah A., Sirish, Padmini, Lau, Victor, Zhang, Yinuo, Fayyaz, Kiran, Singapuri, Anil, Lopez, Javier E., Knowlton, Anne A., Zhang, Xiao-Dong, Chiamvimonvat, Nipavan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545299/
https://ncbi.nlm.nih.gov/pubmed/25995211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.114.002162
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