Local iontophoretic administration of cytotoxic therapies to solid tumors

Parenteral and oral routes have been the traditional methods of administering cytotoxic agents to cancer patients. Unfortunately, the maximum potential effect of these cytotoxic agents has been limited because of systemic toxicity and poor tumor perfusion. In an attempt to improve the efficacy of cy...

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Veröffentlicht in:Sci Transl Med
Hauptverfasser: Byrne, James D., Jajja, Mohammad R. N., O’Neill, Adrian T., Bickford, Lissett R., Keeler, Amanda W., Hyder, Nabeel, Wagner, Kyle, Deal, Allison, Little, Ryan E., Moffitt, Richard A., Stack, Colleen, Nelson, Meredith, Brooks, Christopher R., Lee, William, Luft, J. Chris, Napier, Mary E., Darr, David, Anders, Carey K., Stack, Richard, Tepper, Joel E., Wang, Andrew Z., Zamboni, William C., Yeh, Jen Jen, DeSimone, Joseph M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545246/
https://ncbi.nlm.nih.gov/pubmed/25653220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009951
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