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Generation of Naïve Bovine Induced Pluripotent Stem Cells Using PiggyBac Transposition of Doxycycline-Inducible Transcription Factors

Generation of pluripotent stem cells (PSCs) in large domestic animals has achieved only limited success; most of the PSCs obtained to date have been classified as primed PSCs, which possess very little capacity to produce chimeric offspring. By contrast, mouse PSCs have been classified as naïve PSCs...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kawaguchi, Takamasa, Tsukiyama, Tomoyuki, Kimura, Koji, Matsuyama, Shuichi, Minami, Naojiro, Yamada, Masayasu, Imai, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544884/
https://ncbi.nlm.nih.gov/pubmed/26287611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135403
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