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Blood and immune cell engineering: Cytoskeletal contractility and nuclear rheology impact cell lineage and localization

Clinical success with human hematopoietic stem cell (HSC) transplantation establishes a paradigm for regenerative therapies with other types of stem cells. However, it remains challenging to repair or replace tissues after engineering stem cells in vitro. Recent studies suggest that stem cells sense...

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Pubblicato in:Bioessays
Autori principali: Shin, Jae-Won, Discher, Dennis E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544715/
https://ncbi.nlm.nih.gov/pubmed/25810145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201400166
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