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The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy
Immunoglobulin G (IgG)-based drugs are arguably the most successful class of protein therapeutics due in part to their remarkably long blood circulation. This arises from IgG interaction with the neonatal Fc receptor, FcRn. FcRn is the central regulator of IgG and albumin homeostasis throughout life...
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| Published in: | Adv Drug Deliv Rev |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4544678/ https://ncbi.nlm.nih.gov/pubmed/25703189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2015.02.005 |
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