A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated Ca(V)1.2 Calcium Channel Function

L-type voltage-gated Ca(2+) channels (LTCCs) regulate many physiological functions like muscle contraction, hormone secretion, gene expression, and neuronal excitability. Their activity is strictly controlled by various molecular mechanisms. The pore-forming α(1)-subunit comprises four repeated doma...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Kaur, Gurjot, Pinggera, Alexandra, Ortner, Nadine J., Lieb, Andreas, Sinnegger-Brauns, Martina J., Yarov-Yarovoy, Vladimir, Obermair, Gerald J., Flucher, Bernhard E., Striessnig, Jörg
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Membrane Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543666/
https://ncbi.nlm.nih.gov/pubmed/26100638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645671
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