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Structural determinants of Ca(V)1.3 L-type calcium channel gating

A C-terminal modulatory domain (CTM) tightly regulates the biophysical properties of Ca(v)1.3 L-type Ca(2+) channels, in particular the voltage dependence of activation (V(0.5)) and Ca(2+) dependent inactivation (CDI). A functional CTM is present in the long C-terminus of human and mouse Ca(v)1.3 (C...

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Détails bibliographiques
Auteurs principaux: Lieb, Andreas, Scharinger, Anja, Sartori, Simone, Sinnegger-Brauns, Martina J., Striessnig, Jörg
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431584/
https://ncbi.nlm.nih.gov/pubmed/22760075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.21002
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