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Protein Kinase C Phosphorylation of a γ-Protocadherin C-terminal Lipid Binding Domain Regulates Focal Adhesion Kinase Inhibition and Dendrite Arborization

The γ-protocadherins (γ-Pcdhs) are a family of 22 adhesion molecules with multiple critical developmental functions, including the proper formation of dendritic arbors by forebrain neurons. The γ-Pcdhs bind to and inhibit focal adhesion kinase (FAK) via a constant C-terminal cytoplasmic domain share...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Keeler, Austin B., Schreiner, Dietmar, Weiner, Joshua A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543629/
https://ncbi.nlm.nih.gov/pubmed/26139604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642306
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