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γ-Protocadherins Control Cortical Dendrite Arborization by Regulating the Activity of a FAK/PKC/MARCKS Signaling Pathway

The 22 γ-protocadherins (γ-Pcdhs) potentially specify thousands of distinct homophilic adhesive interactions in the brain. Neonatal lethality of mice lacking the Pcdh-γ gene cluster has, however, precluded analysis of many brain regions. Here, we use a conditional Pcdh-γ allele to restrict mutation...

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Main Authors: Garrett, Andrew M., Schreiner, Dietmar, Lobas, Mark A., Weiner, Joshua A.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582349/
https://ncbi.nlm.nih.gov/pubmed/22542181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.01.028
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