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Atomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor Kinases

G protein-coupled receptor kinases (GRKs) are members of the protein kinase A, G, and C families (AGC) and play a central role in mediating G protein-coupled receptor phosphorylation and desensitization. One member of the family, GRK5, has been implicated in several human pathologies, including hear...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Komolov, Konstantin E., Bhardwaj, Anshul, Benovic, Jeffrey L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543624/
https://ncbi.nlm.nih.gov/pubmed/26032409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.647297
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