Florbetapir PET, FDG PET, and MRI in Down Syndrome Individuals with and without Alzheimer's Dementia

Since Down syndrome (DS) is associated with amyloid β (Aβ) deposition, we characterized imaging measurements of regional fibrillar Aβ burden, cerebral metabolic rate (rCMRgl), gray matter volumes (rGMVs), and age associations in 5 DS with dementia (DS/AD+), 12 DS without dementia (DS/AD-), and 9 nor...

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Bibliographic Details
Published in:Alzheimers Dement
Main Authors: Sabbagh, Marwan N., Chen, Kewei, Rogers, Joseph, Fleisher, Adam S., Liebsack, Carolyn, Bandy, Dan, Belden, Christine, Protas, Hillary, Thiyyagura, Pradeep, Liu, Xiaofen, Roontiva, Auttawut, Luo, Ji, Jacobson, Sandra, Malek-Ahmadi, Michael, Powell, Jessica, Reiman, Eric M.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543530/
https://ncbi.nlm.nih.gov/pubmed/25849033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2015.01.006
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