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A convex formulation for joint RNA isoform detection and quantification from multiple RNA-seq samples

BACKGROUND: Detecting and quantifying isoforms from RNA-seq data is an important but challenging task. The problem is often ill-posed, particularly at low coverage. One promising direction is to exploit several samples simultaneously. RESULTS: We propose a new method for solving the isoform deconvol...

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Опубликовано в: :BMC Bioinformatics
Главные авторы: Bernard, Elsa, Jacob, Laurent, Mairal, Julien, Viara, Eric, Vert, Jean-Philippe
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543468/
https://ncbi.nlm.nih.gov/pubmed/26286719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0695-9
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