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Towards reliable isoform quantification using RNA-SEQ data

BACKGROUND: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address the isoform quantification problem. Given a set of known splice variants, the goal is to estimate the relative abundance...

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Autors principals: Howard, Brian E, Heber, Steffen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863065/
https://ncbi.nlm.nih.gov/pubmed/20438653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-S3-S6
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