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Towards reliable isoform quantification using RNA-SEQ data
BACKGROUND: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address the isoform quantification problem. Given a set of known splice variants, the goal is to estimate the relative abundance...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863065/ https://ncbi.nlm.nih.gov/pubmed/20438653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-S3-S6 |
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