GSK‐3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility

Glycogen synthase kinase 3 (GSK‐3) has been linked to regulation of kinesin‐dependent axonal transport in squid and flies, and to indirect regulation of cytoplasmic dynein. We have now found evidence for direct regulation of dynein by mammalian GSK‐3β in both neurons and non‐neuronal cells. GSK‐3β c...

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Detalhes bibliográficos
Publicado no:Traffic
Main Authors: Gao, Feng J., Hebbar, Sachin, Gao, Xu A., Alexander, Michael, Pandey, Jai P., Walla, Michael D., Cotham, William E., King, Stephen J., Smith, Deanna S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons A/S 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543430/
https://ncbi.nlm.nih.gov/pubmed/26010407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12304
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