GSK‐3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility

Glycogen synthase kinase 3 (GSK‐3) has been linked to regulation of kinesin‐dependent axonal transport in squid and flies, and to indirect regulation of cytoplasmic dynein. We have now found evidence for direct regulation of dynein by mammalian GSK‐3β in both neurons and non‐neuronal cells. GSK‐3β c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Traffic
Prif Awduron: Gao, Feng J., Hebbar, Sachin, Gao, Xu A., Alexander, Michael, Pandey, Jai P., Walla, Michael D., Cotham, William E., King, Stephen J., Smith, Deanna S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley & Sons A/S 2015
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543430/
https://ncbi.nlm.nih.gov/pubmed/26010407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12304
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