Superoxide induces protein oxidation in plasma and TNF-α elevation in macrophage culture: Insights into mechanisms of neurotoxicity following doxorubicin chemotherapy

Chemotherapy-induced cognitive impairment (CICI) is a quality of life-altering consequence of chemotherapy experienced by a large percentage of cancer survivors. Approximately half of FDA-approved anti-cancer drugs are known to produce ROS. Doxorubicin (Dox), a prototypical ROS-generating chemothera...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Keeney, Jeriel T. R., Miriyala, Sumitra, Noel, Teresa, Moscow, Jeffrey A., St Clair, Daret K., Butterfield, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543408/
https://ncbi.nlm.nih.gov/pubmed/26225838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.07.023
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