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Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders

Induction of phosphorylated extracellular-regulated kinase (pERK) is a reliable molecular readout of learning-dependent neuronal activation. Here, we describe a pERK immunohistochemistry protocol to study the profile of hippocampal neuron activation following exposure to a spatial learning task in a...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Provenzano, Giovanni, Pangrazzi, Luca, Poli, Andrea, Berardi, Nicoletta, Bozzi, Yuri
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542650/
https://ncbi.nlm.nih.gov/pubmed/25992917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52919
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