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Lepr(db) Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets

Type 2 diabetes is a chronic disease affecting 382 million people in 2013, and is expected to rise to 592 million by 2035 (1). During the past 2 decades, the role of beta-cell dysfunction in type 2 diabetes has been clearly established (2). Research progress has required methods for the isolation of...

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Библиографические подробности
Опубликовано в: :J Vis Exp
Главные авторы: Do, Oanh H., Low, Jiun T., Thorn, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: MyJove Corporation 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542571/
https://ncbi.nlm.nih.gov/pubmed/25992768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52632
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