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An Aptamer against the Matrix Binding Domain on the Hepatitis B Virus Capsid Impairs Virion Formation

The hepatitis B virus (HBV) particle is an icosahedral nucleocapsid surrounded by a lipid envelope containing viral surface proteins. A small domain (matrix domain [MD]) in the large surface protein L and a narrow region (matrix binding domain [MBD]) including isoleucine 126 on the capsid surface ha...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Orabi, Ahmed, Bieringer, Maria, Geerlof, Arie, Bruss, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542377/
https://ncbi.nlm.nih.gov/pubmed/26136564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00466-15
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