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An Aptamer against the Matrix Binding Domain on the Hepatitis B Virus Capsid Impairs Virion Formation
The hepatitis B virus (HBV) particle is an icosahedral nucleocapsid surrounded by a lipid envelope containing viral surface proteins. A small domain (matrix domain [MD]) in the large surface protein L and a narrow region (matrix binding domain [MBD]) including isoleucine 126 on the capsid surface ha...
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| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4542377/ https://ncbi.nlm.nih.gov/pubmed/26136564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00466-15 |
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