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Characterization of hepatic lipid profiles in a mouse model with nonalcoholic steatohepatitis and subsequent fibrosis

Nonalcoholic steatohepatitis (NASH) is a major health problem since it often leads to hepatocellular carcinoma. However, the underlying mechanisms of NASH development and subsequent fibrosis have yet to be clarified. We compared comprehensive lipidomic profiles between mice with high fat diet (HFD)-...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Saito, Kosuke, Uebanso, Takashi, Maekawa, Keiko, Ishikawa, Masaki, Taguchi, Ryo, Nammo, Takao, Nishimaki-Mogami, Tomoko, Udagawa, Haruhide, Fujii, Masato, Shibazaki, Yuichiro, Yoneyama, Hiroyuki, Yasuda, Kazuki, Saito, Yoshiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542161/
https://ncbi.nlm.nih.gov/pubmed/26289793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12466
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