IL-4/CCL22/CCR4 Axis Controls Regulatory T-Cell Migration That Suppresses Inflammatory Bone Loss in Murine Experimental Periodontitis

Inflammatory bone resorption is a hallmark of periodontitis, and Tregs and Th2 cells are independently associated with disease progression attenuation. In this study, we employed an infection-triggered inflammatory osteolysis model to investigate the mechanisms underlying Treg and Th2 cell migration...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Araujo-Pires, Ana Claudia, Vieira, Andreia Espindola, Francisconi, Carolina Favaro, Biguetti, Claudia Cristina, Glowacki, Andrew, Yoshizawa, Sayuri, Campanelli, Ana Paula, Trombone, Ana Paula Favaro, Sfeir, Charles S., Little, Steven R., Garlet, Gustavo Pompermaier
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542048/
https://ncbi.nlm.nih.gov/pubmed/25264308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2376
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