IL-4/CCL22/CCR4 Axis Controls Regulatory T-Cell Migration That Suppresses Inflammatory Bone Loss in Murine Experimental Periodontitis

Inflammatory bone resorption is a hallmark of periodontitis, and Tregs and Th2 cells are independently associated with disease progression attenuation. In this study, we employed an infection-triggered inflammatory osteolysis model to investigate the mechanisms underlying Treg and Th2 cell migration...

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發表在:J Bone Miner Res
Main Authors: Araujo-Pires, Ana Claudia, Vieira, Andreia Espindola, Francisconi, Carolina Favaro, Biguetti, Claudia Cristina, Glowacki, Andrew, Yoshizawa, Sayuri, Campanelli, Ana Paula, Trombone, Ana Paula Favaro, Sfeir, Charles S., Little, Steven R., Garlet, Gustavo Pompermaier
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542048/
https://ncbi.nlm.nih.gov/pubmed/25264308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2376
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