TRPM7 Regulates Myosin IIA Filament Stability and Protein Localization by Heavy Chain Phosphorylation

Deregulation of myosin II-based contractility contributes to the pathogenesis of human diseases, such as cancer, which underscores the necessity for tight spatial and temporal control of myosin II activity. Recently, we demonstrated that activation of the mammalian α-kinase TRPM7 inhibits myosin II-...

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Publicado en:J Mol Biol
Autores principales: Clark, Kristopher, Middelbeek, Jeroen, Lasonder, Edwin, Dulyaninova, Natalya G., Morrice, Nick A., Ryazanov, Alexey G., Bresnick, Anne R., Figdor, Carl G., van Leeuwen, Frank N.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541798/
https://ncbi.nlm.nih.gov/pubmed/18394644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.02.057
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