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Origin of the classical complement pathway: Lamprey orthologue of mammalian C1q acts as a lectin

The lectin complement pathway in innate immunity is closely related to the classical complement pathway in adaptive immunity, with respect to the structures and functions of their components. Both pathways are initiated by complexes consisting of collagenous proteins and serine proteases of the mann...

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Detalhes bibliográficos
Main Authors: Matsushita, Misao, Matsushita, Akiko, Endo, Yuichi, Nakata, Munehiro, Kojima, Naoya, Mizuochi, Tsuguo, Fujita, Teizo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC454176/
https://ncbi.nlm.nih.gov/pubmed/15218103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402180101
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