Coupling of retinal isomerization to the activation of rhodopsin

Activation of the visual pigment rhodopsin is caused by 11-cis to -trans isomerization of its retinal chromophore. High-resolution solid-state NMR measurements on both rhodopsin and the metarhodopsin II intermediate show how retinal isomerization disrupts helix interactions that lock the receptor of...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Patel, Ashish B., Crocker, Evan, Eilers, Markus, Hirshfeld, Amiram, Sheves, Mordechai, Smith, Steven O.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2004
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454162/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15220479/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402848101
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