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Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4(+)CD45RB(high) T Cells into Immunodeficient Mice

There are many different animal models available for studying the pathogenesis of human inflammatory bowel diseases (IBD), each with its own advantages and disadvantages. We describe here an experimental colitis model that is initiated by adoptive transfer of syngeneic splenic CD4(+)CD45RB(high) T c...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Steinbach, Erin C., Gipson, Gregory R., Sheikh, Shehzad Z.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541583/
https://ncbi.nlm.nih.gov/pubmed/25938395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52533
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