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Δ(9)-Tetrahydrocannabinol attenuates allogeneic host-versus-graft response and delays skin graft rejection through activation of cannabinoid receptor 1 and induction of myeloid-derived suppressor cells

Immune cells have been shown to express cannabinoid receptors and to produce endogenous ligands. Moreover, activation of cannabinoid receptors on immune cells has been shown to trigger potent immunosuppression. Despite such studies, the role of cannabinoids in transplantation, specifically to preven...

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Pubblicato in:J Leukoc Biol
Autori principali: Sido, Jessica M., Nagarkatti, Prakash S., Nagarkatti, Mitzi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541500/
https://ncbi.nlm.nih.gov/pubmed/26034207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0115-030RR
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