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Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties

SUMMARY: Cannabinoid receptor activation by agents such as Δ(9)-tetrahydrocannabinol (THC) is known to trigger immune suppression. Here, we show that administration of THC in mice leads to rapid and massive expansion of CD11b(+)Gr-1(+) myeloid-derived suppressor cells (MDSC) expressing functional ar...

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Bibliografische gegevens
Hoofdauteurs: Hegde, Venkatesh L., Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076065/
https://ncbi.nlm.nih.gov/pubmed/21110319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040667
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