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Gene looping facilitates TFIIH kinase-mediated termination of transcription

TFIIH is a general transcription factor with kinase and helicase activities. The kinase activity resides in the Kin28 subunit of TFIIH. The role of Kin28 kinase in the early steps of transcription is well established. Here we report a novel role of Kin28 in the termination of transcription. We show...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Medler, Scott, Ansari, Athar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541409/
https://ncbi.nlm.nih.gov/pubmed/26286112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12586
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