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Polyphosphate accelerates factor V activation by factor XIa

Factor Va enhances the rate of prothrombin activation by factor Xa by four to five orders of magnitude. Production of initiating levels of factor Va from its precursor, factor V, is a critical event early in haemostasis, as factor V exhibits negligible cofactor activity. While thrombin is the most p...

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Detalhes bibliográficos
Publicado no:Thromb Haemost
Main Authors: Choi, Sharon H., Smith, Stephanie A., Morrissey, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541292/
https://ncbi.nlm.nih.gov/pubmed/25338662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH14-06-0515
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