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Robust hematopoietic progenitor cell commitment in the presence of a conflicting cue

Hematopoietic lineage commitment is regulated by cytokines and master transcription factors, but it remains unclear how a progenitor cell chooses a lineage in the face of conflicting cues. Through transcript counting in megakaryocyte–erythroid progenitors undergoing erythropoiesis, we show that the...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Shah, Najaf A., Levesque, Marshall J., Raj, Arjun, Sarkar, Casim A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541040/
https://ncbi.nlm.nih.gov/pubmed/26159733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.158436
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