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Integrating Extrinsic and Intrinsic Cues into a Minimal Model of Lineage Commitment for Hematopoietic Progenitors

Autoregulation of transcription factors and cross-antagonism between lineage-specific transcription factors are a recurrent theme in cell differentiation. An equally prevalent event that is frequently overlooked in lineage commitment models is the upregulation of lineage-specific receptors, often th...

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Detalhes bibliográficos
Main Authors: Palani, Santhosh, Sarkar, Casim A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736398/
https://ncbi.nlm.nih.gov/pubmed/19911036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000518
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