Curcumin Attenuates Gentamicin-Induced Kidney Mitochondrial Alterations: Possible Role of a Mitochondrial Biogenesis Mechanism

It has been shown that curcumin (CUR), a polyphenol derived from Curcuma longa, exerts a protective effect against gentamicin- (GM-) induced nephrotoxicity in rats, associated with a preservation of the antioxidant status. Although mitochondrial dysfunction is a hallmark in the GM-induced renal inju...

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Udgivet i:Evid Based Complement Alternat Med
Main Authors: Negrette-Guzmán, Mario, García-Niño, Wylly Ramsés, Tapia, Edilia, Zazueta, Cecilia, Huerta-Yepez, Sara, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Aparicio-Trejo, Omar Emiliano, Madero, Magdalena, Pedraza-Chaverri, José
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541007/
https://ncbi.nlm.nih.gov/pubmed/26345660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/917435
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