Sulforaphane Attenuates Gentamicin-Induced Nephrotoxicity: Role of Mitochondrial Protection

Sulforaphane (SFN), an isothiocyanate naturally occurring in Cruciferae, induces cytoprotection in several tissues. Its protective effect has been associated with its ability to induce cytoprotective enzymes through an Nrf2-dependent pathway. Gentamicin (GM) is a widely used antibiotic; nephrotoxici...

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Detalhes bibliográficos
Main Authors: Negrette-Guzmán, Mario, Huerta-Yepez, Sara, Medina-Campos, Omar Noel, Zatarain-Barrón, Zyanya Lucía, Hernández-Pando, Rogelio, Torres, Ismael, Tapia, Edilia, Pedraza-Chaverri, José
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638608/
https://ncbi.nlm.nih.gov/pubmed/23662110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/135314
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