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Effect of Device Design and Formulation on the In Vitro Comparability for Multi-Unit Dose Dry Powder Inhalers

The focus of this investigation was to understand the design space to achieve comparable in vitro performance of two multi-unit dose dry powder inhalers (DPIs)—Flixotide® Accuhaler® (reference product) and MultiHaler® (test product). Flow field, pressure drop and particle trajectories within the tes...

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Détails bibliographiques
Publié dans:AAPS J
Auteurs principaux: Shur, Jagdeep, Saluja, Bhawana, Lee, Sau, Tibbatts, James, Price, Robert
Format: Artigo
Langue:Inglês
Publié: Springer US 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540741/
https://ncbi.nlm.nih.gov/pubmed/25956383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9775-z
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