Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll Like Receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor

Breast milk is the most effective strategy to protect infants against necrotizing enterocolitis (NEC), a devastating disease which is characterized by severe intestinal necrosis. Previous studies have demonstrated that the lipopolysaccharide receptor toll-like receptor 4 (TLR4) plays a critical role...

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Pubblicato in:Mucosal Immunol
Autori principali: Good, Misty, Sodhi, Chhinder P., Egan, Charlotte E., Afrazi, Amin, Jia, Hongpeng, Yamaguchi, Yukihiro, Lu, Peng, Branca, Maria F., Ma, Congrong, Prindle, Thomas, Mielo, Samantha, Pompa, Anthony, Hodzic, Zerina, Ozolek, John A., Hackam, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540669/
https://ncbi.nlm.nih.gov/pubmed/25899687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.30
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