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Alzheimer disease (AD) specific transcription, DNA methylation and splicing in twenty AD associated loci

Genome-wide association studies have identified twenty loci associated with late-onset Alzheimer disease (LOAD). We examined each of the twenty loci, specifically the ±50kb region surrounding the most strongly associated variant, for changes in gene(s) transcription specific to LOAD. Post-mortem hum...

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Detalhes bibliográficos
Publicado no:Mol Cell Neurosci
Main Authors: Humphries, Crystal, Kohli, Martin A., Whitehead, Patrice, Mash, Deborah C., Pericak-Vance, Margaret A., Gilbert, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540636/
https://ncbi.nlm.nih.gov/pubmed/26004081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2015.05.003
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