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Parsimonious Determination of the Optimal Infectious Dose of a Pathogen for Nonhuman Primate Models

The nonhuman primate (NHP) model is often the best experimental model for testing interventions designed to block infection by human pathogens, such as HIV, tuberculosis, and malaria. A physiological model may require the use of a limiting dose of the infectious agent, where only a fraction of anima...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Autor Principal: Roederer, Mario
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540461/
https://ncbi.nlm.nih.gov/pubmed/26285041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005100
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