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Dexamethasone-Mediated Activation of Fibronectin Matrix Assembly Reduces Dispersal of Primary Human Glioblastoma Cells

Despite resection and adjuvant therapy, the 5-year survival for patients with Glioblastoma multiforme (GBM) is less than 10%. This poor outcome is largely attributed to rapid tumor growth and early dispersal of cells, factors that contribute to a high recurrence rate and poor prognosis. An understan...

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Publicat a:PLoS One
Autors principals: Shannon, Stephen, Vaca, Connan, Jia, Dongxuan, Entersz, Ildiko, Schaer, Andrew, Carcione, Jonathan, Weaver, Michael, Avidar, Yoav, Pettit, Ryan, Nair, Mohan, Khan, Atif, Foty, Ramsey A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540426/
https://ncbi.nlm.nih.gov/pubmed/26284619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135951
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