Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901

BACKGROUND: Dispersal of glioblastoma (GBM) cells leads to recurrence and poor prognosis. Accordingly, molecular pathways involved in dispersal are potential therapeutic targets. The mitogen activated protein kinase/extracellular signal regulated kinase (MAPK/ERK) pathway is commonly dysregulated in...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Shannon, Stephen, Jia, Dongxuan, Entersz, Ildiko, Beelen, Paul, Yu, Miao, Carcione, Christian, Carcione, Jonathan, Mahtabfar, Aria, Vaca, Connan, Weaver, Michael, Shreiber, David, Zahn, Jeffrey D., Liu, Liping, Lin, Hao, Foty, Ramsey A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303286/
https://ncbi.nlm.nih.gov/pubmed/28187762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3107-x
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