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Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

Herein we report that the VEGFR/PDGFR kinase inhibitor sunitinib/SU11248 can accelerate metastatic tumor growth and decrease overall survival in mice receiving short-term therapy in various metastasis assays, including after intravenous injection of tumor cells or after removal of primary orthotopic...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Ebos, John M.L., Lee, Christina R., Cruz-Munoz, William, Bjarnason, Georg A., Christensen, James G., Kerbel, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540346/
https://ncbi.nlm.nih.gov/pubmed/19249681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.01.021
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