Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

Herein we report that the VEGFR/PDGFR kinase inhibitor sunitinib/SU11248 can accelerate metastatic tumor growth and decrease overall survival in mice receiving short-term therapy in various metastasis assays, including after intravenous injection of tumor cells or after removal of primary orthotopic...

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Bibliografische gegevens
Gepubliceerd in:Cancer Cell
Hoofdauteurs: Ebos, John M.L., Lee, Christina R., Cruz-Munoz, William, Bjarnason, Georg A., Christensen, James G., Kerbel, Robert S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540346/
https://ncbi.nlm.nih.gov/pubmed/19249681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.01.021
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